Linked Life Data

15195893

Source:http://linkedlifedata.com/resource/pubmed/id/15195893

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2004-6-15
pubmed:abstractText
Large-volume paracentesis induces early beneficial haemodynamic changes that may be shortly followed by a disorder known as paracentesis-induced circulatory dysfunction, characterized by a marked activation of the renin-angiotensin axis. Evidence is accumulating however that this disorder is secondary to an accentuation of an already established arteriolar vasodilatation. The causes of this syndrome are probably multiple and may include the dynamics of paracentesis (the rate of ascitic fluid extraction), release of nitric oxide from the vascular endothelium and mechanical modifications due to abdominal decompression. Patients developing this syndrome are prone to a faster reaccumulation of ascites, renal impairment and shorter survival. Plasma volume expansion after paracentesis reduces the incidence of this disorder. Preliminary evidence suggests that other approaches, such as the use of splanchnic vasoconstrictors or modulating the rate of ascitic fluid extraction, could be also effective, although more studies are needed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0954-691X
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
295-8
pubmed:dateRevised
2009-10-16
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Understanding the mechanisms of paracentesis-induced crculatory dysfunction.
pubmed:affiliation
Department of Gastroenterology, Hospital Universitario de Elche, Hospital General Universitario, Alicante, Spain.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't