rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2004-5-28
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pubmed:abstractText |
This review will survey recent findings on the cholesterol transport and scavenger functions of scavenger receptor BI. Although scavenger receptor BI and CD36 bind many of the same ligands, these two receptors have very specific lipid transport functions: CD36 facilitates the uptake of long chain fatty acids and SR-BI mediates the transport of cholesterol and cholesteryl ester from HDL particles. Scavenger receptor BI is a physiologically relevant HDL receptor that, along with HDL, is protective against cardiovascular disease. Its atheroprotective role has been hypothesized to be due to its function in the reverse cholesterol transport pathway.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD36,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Immunologic,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Lipoprotein,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Scavenger,
http://linkedlifedata.com/resource/pubmed/chemical/high density lipoprotein receptors
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0957-9672
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
287-95
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15166784-Animals,
pubmed-meshheading:15166784-Antigens, CD36,
pubmed-meshheading:15166784-Arteriosclerosis,
pubmed-meshheading:15166784-Biological Transport,
pubmed-meshheading:15166784-Cardiovascular Diseases,
pubmed-meshheading:15166784-Cholesterol,
pubmed-meshheading:15166784-Humans,
pubmed-meshheading:15166784-Lipoproteins, HDL,
pubmed-meshheading:15166784-Receptors, Immunologic,
pubmed-meshheading:15166784-Receptors, Lipoprotein,
pubmed-meshheading:15166784-Receptors, Scavenger
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pubmed:year |
2004
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pubmed:articleTitle |
Scavenger receptor BI: a scavenger receptor with a mission to transport high density lipoprotein lipids.
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pubmed:affiliation |
Department of Pharmacological Sciences, University Medical Center, State University of New York at Stony Brook, Stony Brook, NY 11794-8651, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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