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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2004-5-26
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pubmed:abstractText |
Prior work has shown that autoimmune uveoretinitis develops spontaneously in CD25(+)CD4(+) regulatory T-cell-depleted mice (Tr-depleted mice). In this study, the generation of autoantibodies and autoreactive T-cells specific to retinal antigens was examined in Tr-depleted mice with uveoretinitis, and the pathogenic and immunogenic abilities of the autoreactive T cells were evaluated.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Arrestin,
http://linkedlifedata.com/resource/pubmed/chemical/Autoantibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Autoantigens,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Granulocyte-Macrophage...,
http://linkedlifedata.com/resource/pubmed/chemical/Immunoglobulin G,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-gamma,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-10,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Interleukin-2
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0146-0404
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1879-86
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15161853-Adoptive Transfer,
pubmed-meshheading:15161853-Animals,
pubmed-meshheading:15161853-Arrestin,
pubmed-meshheading:15161853-Autoantibodies,
pubmed-meshheading:15161853-Autoantigens,
pubmed-meshheading:15161853-Autoimmune Diseases,
pubmed-meshheading:15161853-CD4-Positive T-Lymphocytes,
pubmed-meshheading:15161853-Cattle,
pubmed-meshheading:15161853-DNA-Binding Proteins,
pubmed-meshheading:15161853-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:15161853-Flow Cytometry,
pubmed-meshheading:15161853-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:15161853-Granulocyte-Macrophage Colony-Stimulating Factor,
pubmed-meshheading:15161853-Immunoglobulin G,
pubmed-meshheading:15161853-Interferon-gamma,
pubmed-meshheading:15161853-Interleukin-10,
pubmed-meshheading:15161853-Lymphocyte Depletion,
pubmed-meshheading:15161853-Mice,
pubmed-meshheading:15161853-Mice, Inbred C57BL,
pubmed-meshheading:15161853-Mice, Nude,
pubmed-meshheading:15161853-Nuclear Proteins,
pubmed-meshheading:15161853-Photoreceptor Cells, Vertebrate,
pubmed-meshheading:15161853-Receptors, Interleukin-2,
pubmed-meshheading:15161853-Retinitis,
pubmed-meshheading:15161853-Th1 Cells,
pubmed-meshheading:15161853-Uveitis
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pubmed:year |
2004
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pubmed:articleTitle |
Immune responses to retinal self-antigens in CD25(+)CD4(+) regulatory T-cell-depleted mice.
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pubmed:affiliation |
Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan. takeuchi@tokyo-med.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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