Linked Life Data

15157441

Source:http://linkedlifedata.com/resource/pubmed/id/15157441

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2004-5-25
pubmed:abstractText
Studies using a variety of microscopy-based approaches have led to a consensus that most cell-surface proteins are highly mobile and diffuse rapidly within fenced microdomains. Little attention, however, has so far been given to the analysis of the mobility of intracellular membrane proteins because of their comparative inaccessibility. Recent advances in microinjection, confocal microscopy and the construction of epitope-tagged proteins or of hybrids with an intrinsically fluorescent protein have allowed intracellular membrane proteins to be studied using approaches previously applied to characterize the mobility of cell-surface proteins. Confocal fluorescence recovery after photobleaching (c-FRAP) experiments show that intracellular membrane proteins may also be highly mobile.
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Aug
pubmed:issn
0962-8924
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
321-4
pubmed:year
1996
pubmed:articleTitle
Probing the mobility of membrane proteins inside the cell.
pubmed:affiliation
Dept of Biochemistry, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0308, USA.
pubmed:publicationType
Journal Article