Source:http://linkedlifedata.com/resource/pubmed/id/15149636
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
2004-5-19
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pubmed:abstractText |
Three new porphyrin-DNA cross-linking conjugates 8, 9, and 10 have been synthesized. Their photoinduced DNA cleavage activity have been studied. The IC(50) values to THP-1 cells in the presence of porphyrin derivatives 8, 9, and 10 with photoirradiation were 5.6, 88.4, and 61.8 nM, respectively.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0960-894X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
21
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3013-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15149636-Antineoplastic Agents,
pubmed-meshheading:15149636-Cell Line, Tumor,
pubmed-meshheading:15149636-Cell Survival,
pubmed-meshheading:15149636-Cross-Linking Reagents,
pubmed-meshheading:15149636-DNA,
pubmed-meshheading:15149636-DNA Damage,
pubmed-meshheading:15149636-Humans,
pubmed-meshheading:15149636-Porphyrins
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pubmed:year |
2004
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pubmed:articleTitle |
Porphyrin-DNA cross-linking agent hybrids: chemical synthesis and biological studies.
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pubmed:affiliation |
College of Chemistry and Molecular Sciences, Wuhan University, Hubei, Wuhan 430072, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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