| pubmed-article:15147902 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15147902 | lifeskim:mentions | umls-concept:C0008377 | lld:lifeskim |
| pubmed-article:15147902 | lifeskim:mentions | umls-concept:C0003591 | lld:lifeskim |
| pubmed-article:15147902 | lifeskim:mentions | umls-concept:C0101671 | lld:lifeskim |
| pubmed-article:15147902 | lifeskim:mentions | umls-concept:C1824201 | lld:lifeskim |
| pubmed-article:15147902 | lifeskim:mentions | umls-concept:C2246761 | lld:lifeskim |
| pubmed-article:15147902 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:15147902 | lifeskim:mentions | umls-concept:C1708715 | lld:lifeskim |
| pubmed-article:15147902 | lifeskim:mentions | umls-concept:C2346689 | lld:lifeskim |
| pubmed-article:15147902 | pubmed:issue | 1-3 | lld:pubmed |
| pubmed-article:15147902 | pubmed:dateCreated | 2004-5-18 | lld:pubmed |
| pubmed-article:15147902 | pubmed:abstractText | Here, we identify ADP-ribosylation factor (ARF)-like 7 (ARL7) as the only ARF- and ARL-family member whose mRNA-expression is induced by liver X-receptor/retinoid X-receptor agonists or cholesterol loading in human macrophages. Moreover, subcellular distribution of mutant and wild type ARL7-enhanced green fluorescent protein (EGFP) supports that ARL7 may be involved in a vesicular transport step between a perinuclear compartment and the plasma membrane. Therefore, we investigated the effect of ARL7 over-expression on the cholesterol secretory pathway. We found that expression of wild type and dominant active ARL7-EGFP stimulated the rate of apolipoprotein AI-specific cholesterol efflux 1.7- and 2.8-fold. In contrast, expression of the dominant negative form of ARL7-EGFP led to approximately 50% inhibition of cholesterol efflux. This data is consistent with a model in which ARL7 is involved in transport between a perinuclear compartment and the plasma membrane apparently linked to the ABCA1-mediated cholesterol secretion pathway. | lld:pubmed |
| pubmed-article:15147902 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15147902 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15147902 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15147902 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15147902 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15147902 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15147902 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15147902 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15147902 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15147902 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15147902 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15147902 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15147902 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15147902 | pubmed:month | May | lld:pubmed |
| pubmed-article:15147902 | pubmed:issn | 0014-5793 | lld:pubmed |
| pubmed-article:15147902 | pubmed:author | pubmed-author:AssmannGerdG | lld:pubmed |
| pubmed-article:15147902 | pubmed:author | pubmed-author:CullenPaulP | lld:pubmed |
| pubmed-article:15147902 | pubmed:author | pubmed-author:EngelThomasT | lld:pubmed |
| pubmed-article:15147902 | pubmed:author | pubmed-author:RustStephanS | lld:pubmed |
| pubmed-article:15147902 | pubmed:author | pubmed-author:HobohmUweU | lld:pubmed |
| pubmed-article:15147902 | pubmed:author | pubmed-author:SeedorfUdoU | lld:pubmed |
| pubmed-article:15147902 | pubmed:author | pubmed-author:LorkowskiStef... | lld:pubmed |
| pubmed-article:15147902 | pubmed:author | pubmed-author:LuekenAloysA | lld:pubmed |
| pubmed-article:15147902 | pubmed:author | pubmed-author:BodeGüntherG | lld:pubmed |
| pubmed-article:15147902 | pubmed:author | pubmed-author:SchlueterBern... | lld:pubmed |
| pubmed-article:15147902 | pubmed:author | pubmed-author:PechMichaelM | lld:pubmed |
| pubmed-article:15147902 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15147902 | pubmed:day | 21 | lld:pubmed |
| pubmed-article:15147902 | pubmed:volume | 566 | lld:pubmed |
| pubmed-article:15147902 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15147902 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15147902 | pubmed:pagination | 241-6 | lld:pubmed |
| pubmed-article:15147902 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:15147902 | pubmed:meshHeading | pubmed-meshheading:15147902... | lld:pubmed |
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| pubmed-article:15147902 | pubmed:meshHeading | pubmed-meshheading:15147902... | lld:pubmed |
| pubmed-article:15147902 | pubmed:meshHeading | pubmed-meshheading:15147902... | lld:pubmed |
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| pubmed-article:15147902 | pubmed:meshHeading | pubmed-meshheading:15147902... | lld:pubmed |
| pubmed-article:15147902 | pubmed:meshHeading | pubmed-meshheading:15147902... | lld:pubmed |
| pubmed-article:15147902 | pubmed:meshHeading | pubmed-meshheading:15147902... | lld:pubmed |
| pubmed-article:15147902 | pubmed:meshHeading | pubmed-meshheading:15147902... | lld:pubmed |
| pubmed-article:15147902 | pubmed:meshHeading | pubmed-meshheading:15147902... | lld:pubmed |
| pubmed-article:15147902 | pubmed:meshHeading | pubmed-meshheading:15147902... | lld:pubmed |
| pubmed-article:15147902 | pubmed:meshHeading | pubmed-meshheading:15147902... | lld:pubmed |
| pubmed-article:15147902 | pubmed:meshHeading | pubmed-meshheading:15147902... | lld:pubmed |
| pubmed-article:15147902 | pubmed:meshHeading | pubmed-meshheading:15147902... | lld:pubmed |
| pubmed-article:15147902 | pubmed:meshHeading | pubmed-meshheading:15147902... | lld:pubmed |
| pubmed-article:15147902 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:15147902 | pubmed:articleTitle | ADP-ribosylation factor (ARF)-like 7 (ARL7) is induced by cholesterol loading and participates in apolipoprotein AI-dependent cholesterol export. | lld:pubmed |
| pubmed-article:15147902 | pubmed:affiliation | Institut für Arterioskleroseforschung, Westfälische Wilhelms-Universität, Domagkstr. 3, D-48149 Münster, Germany. engeltho@uni-muenster.de | lld:pubmed |
| pubmed-article:15147902 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15147902 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:10123 | entrezgene:pubmed | pubmed-article:15147902 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15147902 | lld:pubmed |
