rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
|
pubmed:dateCreated |
2004-5-11
|
pubmed:abstractText |
Mutations in the GATA-1 gene have been identified in patients with familial macrothrombocytopenia and Down's syndrome patients with a transient myeloproliferative disorder and/or acute megakaryoblastic leukemia. We screened this gene in 46 patients with essential thrombocythemia and identified only a common single nucleotide polymorphism that is unlikely to be of pathological significance.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
1592-8721
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
89
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
613-5
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:15136229-Animals,
pubmed-meshheading:15136229-Female,
pubmed-meshheading:15136229-GATA1 Transcription Factor,
pubmed-meshheading:15136229-HL-60 Cells,
pubmed-meshheading:15136229-Humans,
pubmed-meshheading:15136229-Mice,
pubmed-meshheading:15136229-Mice, Knockout,
pubmed-meshheading:15136229-Polymerase Chain Reaction,
pubmed-meshheading:15136229-Polymorphism, Single Nucleotide,
pubmed-meshheading:15136229-Thrombocythemia, Essential
|
pubmed:year |
2004
|
pubmed:articleTitle |
No mutations in the GATA-1 gene detected in patients with acquired essential thrombocythemia.
|
pubmed:publicationType |
Letter,
Research Support, Non-U.S. Gov't
|