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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2004-5-4
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pubmed:abstractText |
PreS2-defective hepatitis B virus (HBV) variants may emerge during chronic HBV infection. These variants carry mutation(s) at the ATG-start-codon and/or in-frame deletion into the preS2 genomic region and are commonly detected by sequencing analyses. We evaluated the prevalence of these variants in a large series of chronic HBV infected patients through non-sequencing molecular approaches.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0168-8278
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
515-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15123368-Carcinoma, Hepatocellular,
pubmed-meshheading:15123368-Carrier State,
pubmed-meshheading:15123368-Codon, Initiator,
pubmed-meshheading:15123368-Electrophoresis, Agar Gel,
pubmed-meshheading:15123368-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:15123368-Gene Deletion,
pubmed-meshheading:15123368-Gene Frequency,
pubmed-meshheading:15123368-Genetic Techniques,
pubmed-meshheading:15123368-Genetic Variation,
pubmed-meshheading:15123368-Genome, Viral,
pubmed-meshheading:15123368-Hepatitis B, Chronic,
pubmed-meshheading:15123368-Hepatitis B Surface Antigens,
pubmed-meshheading:15123368-Hepatitis B virus,
pubmed-meshheading:15123368-Humans,
pubmed-meshheading:15123368-Liver Cirrhosis,
pubmed-meshheading:15123368-Liver Diseases,
pubmed-meshheading:15123368-Liver Neoplasms,
pubmed-meshheading:15123368-Mutation,
pubmed-meshheading:15123368-Polymerase Chain Reaction,
pubmed-meshheading:15123368-Prevalence,
pubmed-meshheading:15123368-Protein Precursors,
pubmed-meshheading:15123368-Sensitivity and Specificity,
pubmed-meshheading:15123368-Severity of Illness Index
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pubmed:year |
2004
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pubmed:articleTitle |
Non-sequencing molecular approaches to identify preS2-defective hepatitis B virus variants proved to be associated with severe liver diseases.
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pubmed:affiliation |
Unità di Epatologia Clinica e Biomolecolare, Dipartimento di Medicina Interna, Policlinico Universitario di Messina, 98124 Messina, Italy. raimondo@unime.it
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pubmed:publicationType |
Journal Article
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