rdf:type |
|
lifeskim:mentions |
umls-concept:C0006142,
umls-concept:C0008976,
umls-concept:C0034656,
umls-concept:C0039286,
umls-concept:C0043210,
umls-concept:C0087111,
umls-concept:C0205179,
umls-concept:C0232970,
umls-concept:C0279025,
umls-concept:C0935916,
umls-concept:C1707455
|
pubmed:issue |
9
|
pubmed:dateCreated |
2004-4-30
|
pubmed:abstractText |
To evaluate the efficacy and tolerability of fulvestrant (Faslodex; AstraZeneca Pharmaceuticals LP, Wilmington, DE), a new estrogen receptor (ER) antagonist that downregulates ER and has no agonist effects, versus tamoxifen, an antiestrogen with agonist and antagonist effects, for the treatment of advanced breast cancer in postmenopausal women.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0732-183X
|
pubmed:author |
pubmed-author:AbramPaulP,
pubmed-author:BajettaEmilioE,
pubmed-author:DimeryIsaiahI,
pubmed-author:ElledgeRichardR,
pubmed-author:HowellAnthonyA,
pubmed-author:LichinitserMikhail RMR,
pubmed-author:MorrisCharlesC,
pubmed-author:OsborneC KentCK,
pubmed-author:RobertsonJohn F RJF,
pubmed-author:WatanabeToruT,
pubmed-author:WebsterAlanA
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
22
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1605-13
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15117982-Administration, Oral,
pubmed-meshheading:15117982-Adult,
pubmed-meshheading:15117982-Aged,
pubmed-meshheading:15117982-Aged, 80 and over,
pubmed-meshheading:15117982-Antineoplastic Agents, Hormonal,
pubmed-meshheading:15117982-Breast Neoplasms,
pubmed-meshheading:15117982-Disease Progression,
pubmed-meshheading:15117982-Disease-Free Survival,
pubmed-meshheading:15117982-Double-Blind Method,
pubmed-meshheading:15117982-Estradiol,
pubmed-meshheading:15117982-Female,
pubmed-meshheading:15117982-Humans,
pubmed-meshheading:15117982-Injections, Intramuscular,
pubmed-meshheading:15117982-Middle Aged,
pubmed-meshheading:15117982-Receptors, Estrogen,
pubmed-meshheading:15117982-Receptors, Progesterone,
pubmed-meshheading:15117982-Tamoxifen
|
pubmed:year |
2004
|
pubmed:articleTitle |
Comparison of fulvestrant versus tamoxifen for the treatment of advanced breast cancer in postmenopausal women previously untreated with endocrine therapy: a multinational, double-blind, randomized trial.
|
pubmed:affiliation |
Christie Hospital and Holt Radium Institute, Manchester, UK. maria.parker@christie-tr.nwest.nhs.uk
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|