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pubmed:abstractText |
We have provided evidence that glucagon-like peptide-1, a potential therapeutic agent in the treatment of diabetes, activates phosphatidylinositol-3 kinase/protein kinase B signalling in the pancreatic beta cell. Since this pathway promotes cell survival in a variety of systems, we tested whether glucagon-like peptide-1 protects beta cells against cell death induced by elevated glucose and/or non-esterified fatty acids.
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pubmed:affiliation |
Molecular Nutrition Unit, Department of Nutrition, University of Montreal, CR-CHUM, Pavillon de Sève, Montreal, PQ, Canada.
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