Protein farnesyltransferase inhibitor (SCH 66336) abolishes NF-kappaB activation induced by various carcinogens and inflammatory stimuli leading to suppression of NF-kappaB-regulated gene expression and up-regulation of apoptosis.

Source:http://linkedlifedata.com/resource/pubmed/id/15090542

J. Biol. Chem. 2004 Jun 18 279 25 26287-99

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PMID
15090542