Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-9-24
pubmed:abstractText
At day one and on the following day subarachnoid haemorrhage (SAH) was induced in SPF-rats by injection of a mixture of autologous blood and CSF into the cisterna magna. At day eight the animals were treated with Nimodipine. Extracellular calcium and -potassium concentrations as well as local cerebral blood flow and arterial blood pressure were measured simultaneously. The cerebral vasospasm was documented by corrosion casts. The control group underwent the same procedure without previous SAH. Cerebral vasospasm still exists after nimodipine infusion as it can be demonstrated by corrosion casts showing an intensive grooving and a vertical relief. Extracellular potassium and calcium concentration are higher in the SAH-group than in the control-group. The influence of nimodipine to blood pressure and cerebral blood flow is more impressive in rats with SAH showing a significant decrease in blood pressure and local blood flow.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0028-3819
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
99-102
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Vasospasm after experimentally induced subarachnoid haemorrhage and treatment with nimodipine.
pubmed:affiliation
Department of Neurosurgery, Hannover Medical School.
pubmed:publicationType
Journal Article