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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2004-4-9
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pubmed:abstractText |
The aim of this study is to compare glucose metabolism and hypoxia in four different tumor types using positron emission tomography (PET). (18)F-labeled fluorodeoxyglucose (FDG) evaluates energy metabolism, whereas the uptake of (18)F-labeled fluoromisonidazole (FMISO) is proportional to tissue hypoxia. Although acute hypoxia results in accelerated glycolysis, cellular metabolism is slowed in chronic hypoxia, prompting us to look for discordance between FMISO and FDG uptake.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2245-52
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15073099-Anoxia,
pubmed-meshheading:15073099-Cell Line, Tumor,
pubmed-meshheading:15073099-Fluorodeoxyglucose F18,
pubmed-meshheading:15073099-Glucose,
pubmed-meshheading:15073099-Glycolysis,
pubmed-meshheading:15073099-Humans,
pubmed-meshheading:15073099-Image Processing, Computer-Assisted,
pubmed-meshheading:15073099-Neoplasm Metastasis,
pubmed-meshheading:15073099-Neoplasms,
pubmed-meshheading:15073099-Positron-Emission Tomography,
pubmed-meshheading:15073099-Radiopharmaceuticals
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pubmed:year |
2004
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pubmed:articleTitle |
Hypoxia and glucose metabolism in malignant tumors: evaluation by [18F]fluoromisonidazole and [18F]fluorodeoxyglucose positron emission tomography imaging.
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pubmed:affiliation |
Department of Radiology, University of Washington, Seattle, 98195, USA. rajan@u.washington.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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