Linked Life Data

15061192

Source:http://linkedlifedata.com/resource/pubmed/id/15061192

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2004-4-5
pubmed:abstractText
Umbilical cord blood (UCB) is potentially an attractive new source of hematopoietic stem cells. The extensive and ready availability of UCB offers important logistical advantages compared with traditional unrelated bone marrow. However, the initial concern about engraftment due to the low number of progenitor cells contained in a UCB unit, has limited the use of UCB, mainly for adult patients. In this review, we summarize the most important data available regarding the main aspects of unrelated-donor cord blood transplantation (UD-CBT) in adult patients. We will review the characteristics of UCB and their practical implications, the outcomes of and clinical results after UD-CBT used for hematological malignancies, and the current advances in UD-CBT designed to optimize this procedure. Current data confirm that UD-CBT is a reasonable alternative for those patients lacking a matched bone-marrow donor.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1042-8194
pubmed:author
pubmed:issnType
Print
pubmed:volume
45
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
11-8
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Unrelated-donor cord blood transplantation for adult hematological malignancies.
pubmed:affiliation
Bone Marrow Transplant Unit, Hematology Department, Hospital Universitario La Fe, Valencia, Spain.
pubmed:publicationType
Journal Article, Review