rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
2004-4-1
|
pubmed:abstractText |
Celiac disease is caused by the interaction of multiple genes and environmental factors. Inheritance of the disease shows a complex pattern with a 10% sibling recurrence risk. The HLA-region is a major genetic risk locus in celiac disease, but genes outside this region are expected to contribute to the disease risk as well. The aim of this study was to identify the loci causing celiac disease in one large Dutch family with apparent dominant transmission of the disease.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0002-9270
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
99
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
466-71
|
pubmed:dateRevised |
2010-11-18
|
pubmed:meshHeading |
pubmed-meshheading:15056087-Adolescent,
pubmed-meshheading:15056087-Adult,
pubmed-meshheading:15056087-Aged,
pubmed-meshheading:15056087-Aged, 80 and over,
pubmed-meshheading:15056087-Celiac Disease,
pubmed-meshheading:15056087-Child,
pubmed-meshheading:15056087-Chromosomes, Human, Pair 6,
pubmed-meshheading:15056087-Chromosomes, Human, Pair 9,
pubmed-meshheading:15056087-Female,
pubmed-meshheading:15056087-Genetic Linkage,
pubmed-meshheading:15056087-Genome, Human,
pubmed-meshheading:15056087-Humans,
pubmed-meshheading:15056087-Male,
pubmed-meshheading:15056087-Middle Aged,
pubmed-meshheading:15056087-Netherlands,
pubmed-meshheading:15056087-Pedigree
|
pubmed:year |
2004
|
pubmed:articleTitle |
A genomewide screen in a four-generation Dutch family with celiac disease: evidence for linkage to chromosomes 6 and 9.
|
pubmed:affiliation |
Department of Biomedical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|