Linked Life Data

1504146

Source:http://linkedlifedata.com/resource/pubmed/id/1504146

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1992-9-23
pubmed:abstractText
Although extensive investigations into the role of neutrophils and their products in tissue injury have been conducted, very little work has been carried out on the role of polypeptide cytokines in the regulation of neutrophil-mediated tissue damage. A range of cytokines are known to promote a wide variety of functions of the neutrophil, including neutrophil adhesion, surface receptor expression, ODRS production, and release of lysosomal constituents. Evidence has been presented to show that these products, either singly or in combination, cause tissue injury. At this stage, TNF alpha and TNF beta are cytokines which have been shown to regulate neutrophil tissue injury. From this work it is suggested that TNFs promote neutrophil-mediated tissue damage.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0092-6019
pubmed:author
pubmed:issnType
Print
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
499-521
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Mechanisms of host tissue damage by cytokine-activated neutrophils.
pubmed:affiliation
University of Adelaide, South Australia.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't