rdf:type |
|
lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2004-3-25
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pubmed:abstractText |
Trk1 and Trk2 are the major K(+) transport systems in Schizosaccharomyces pombe. Both transporters individually seem to be able to cope with K(+) requirements of the cells under normal conditions, since only the double mutant shows defective K(+) transport and defective growth at limiting K(+) concentrations. We have studied in detail the role of SpTrk1 and SpTrk2 under different ion stress conditions. Results show that the strain with only Trk1 (trk1(+)) is less sensitive to Li(+) and to hygromycin B, it grows better at low K(+) and it survives longer in a medium without K(+) than the strain expressing only Trk2 (trk2(+)). We conclude that Trk1 contributes more efficiently than Trk2 to the performance of the fission yeast under ion stress conditions. In the wild type both trk1(+) and trk2(+) genes are expressed and probably collaborate for the performance of the cells.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cation Transport Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Culture Media,
http://linkedlifedata.com/resource/pubmed/chemical/Fungal Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Hygromycin B,
http://linkedlifedata.com/resource/pubmed/chemical/Lithium,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium,
http://linkedlifedata.com/resource/pubmed/chemical/Rubidium,
http://linkedlifedata.com/resource/pubmed/chemical/Saccharomyces cerevisiae Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/TRK1 protein, S cerevisiae,
http://linkedlifedata.com/resource/pubmed/chemical/TRK2 protein, S cerevisiae
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1567-1356
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
619-24
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
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pubmed:year |
2004
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pubmed:articleTitle |
On the role of Trk1 and Trk2 in Schizosaccharomyces pombe under different ion stress conditions.
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pubmed:affiliation |
Departamento de Microbiologiá, Universidad de Córdoba, Campus Universitario de Rabanales Edif. Severo Ochoa, 14071 Córdoba, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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