Linked Life Data

14987979

Source:http://linkedlifedata.com/resource/pubmed/id/14987979

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2004-2-27
pubmed:abstractText
In this study is presented the phosphorotioate nucleotide compound (1) possessing an unusual moiety with a chiral P and a Se atoms double bonded. It required a force field parameterization for carrying out standard molecular mechanics calculations. A new set of MMFF parameters was developed and applied for the complete conformational search of the diastereoisomers, using both Monte Carlo and molecular dynamics, with the purpose to validate them by the comparison between calculated structural properties and NMR measurements.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0014-827X
pubmed:author
pubmed:issnType
Print
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
169-73
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Conformational search of antisense nucleotides. Part 2.
pubmed:affiliation
Dipartimento di Scienze Farmacobiologiche, Università di Catanzaro "Magna Graecia", Complesso Ninì Barbieri, Roccelletta di Borgia (CZ) 88021, Italy. alcaro@unicz.it
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't