Source:http://linkedlifedata.com/resource/pubmed/id/14984431
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2004-2-26
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pubmed:abstractText |
Individuals whose platelets are resistant to the antiaggregatory effects of insulin in vitro are also resistant to the antiaggregatory effects of nitroglycerin (GTN). We have previously shown that insulin acutely diminishes central wave reflection in large arteries and that this action of insulin is blunted in insulin-resistant subjects. However, as yet, no studies have compared the haemodynamic effects of insulin and GTN on large arterial function in the same group of subjects. The aim of this study was to determine whether resistance to the haemodynamic effects of insulin is a defect specific to insulin or whether individuals resistant to the vascular actions of insulin are also resistant to GTN.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0014-2972
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-8
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:14984431-Administration, Sublingual,
pubmed-meshheading:14984431-Adult,
pubmed-meshheading:14984431-Aorta,
pubmed-meshheading:14984431-Blood Pressure,
pubmed-meshheading:14984431-Blood Pressure Determination,
pubmed-meshheading:14984431-Brachial Artery,
pubmed-meshheading:14984431-Cross-Sectional Studies,
pubmed-meshheading:14984431-Dose-Response Relationship, Drug,
pubmed-meshheading:14984431-Female,
pubmed-meshheading:14984431-Heart Rate,
pubmed-meshheading:14984431-Humans,
pubmed-meshheading:14984431-Hypoglycemic Agents,
pubmed-meshheading:14984431-Insulin,
pubmed-meshheading:14984431-Male,
pubmed-meshheading:14984431-Middle Aged,
pubmed-meshheading:14984431-Nitroglycerin,
pubmed-meshheading:14984431-Vasodilator Agents
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pubmed:year |
2004
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pubmed:articleTitle |
Comparison of in vivo effects of nitroglycerin and insulin on the aortic pressure waveform.
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pubmed:affiliation |
Department of Medicine, Division of Diabetes, University of Helsinki, Finland. jukka.westerbacka@helsinki.fi
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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