Source:http://linkedlifedata.com/resource/pubmed/id/14980675
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2004-2-24
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pubmed:abstractText |
Radiolabeled antimitotic agents [11C]T138067 and [18F]T138067 have been synthesized for evaluation as new potential positron emission tomography (PET) biomarkers for cancer imaging. In vivo biodistribution and micro-PET imaging of [11C]T138067 were performed in breast cancer animal models MCF-7 transfected with IL-1alpha implanted athymic mice and MDA-MB-435 implanted athymic mice. The results suggest that the uptakes of [11C]T138067 in both MCF-7 transfected with IL-1alpha tumor and MDA-MB-435 tumor are non-specific binding.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0960-894X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
8
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1247-51
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:14980675-Animals,
pubmed-meshheading:14980675-Antineoplastic Agents,
pubmed-meshheading:14980675-Biological Availability,
pubmed-meshheading:14980675-Carbon Radioisotopes,
pubmed-meshheading:14980675-Mice,
pubmed-meshheading:14980675-Mice, Nude,
pubmed-meshheading:14980675-Sulfonamides,
pubmed-meshheading:14980675-Tissue Distribution,
pubmed-meshheading:14980675-Tomography, Emission-Computed,
pubmed-meshheading:14980675-Xenograft Model Antitumor Assays
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pubmed:year |
2004
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pubmed:articleTitle |
Synthesis, biodistribution and micro-PET imaging of radiolabeled antimitotic agent T138067 analogues.
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pubmed:affiliation |
Department of Radiology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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