rdf:type |
|
lifeskim:mentions |
umls-concept:C0013216,
umls-concept:C0027651,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0681814,
umls-concept:C0871261,
umls-concept:C1511790,
umls-concept:C1516044,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1710493,
umls-concept:C2911692
|
pubmed:issue |
2
|
pubmed:dateCreated |
2004-2-12
|
pubmed:abstractText |
Annexin V (annexin A5), a human protein with a high affinity for phosphatidylserine, labeled with (99m)Tc can detect apoptosis in vivo. In the repetitive detection of apoptosis with (99m)Tc-annexin V, however, the specific binding of annexin V to phosphatidylserine might affect the subsequent detection of apoptosis with this compound. To determine whether there is interference with repetitive doses of annexin V, we evaluated the effects of previous administration of cold annexin V on accumulation of (99m)Tc-annexin V in tumors in an experimental tumor model.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0161-5505
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
45
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
309-12
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:14960654-Animals,
pubmed-meshheading:14960654-Annexin A5,
pubmed-meshheading:14960654-Antineoplastic Agents, Alkylating,
pubmed-meshheading:14960654-Apoptosis,
pubmed-meshheading:14960654-Cyclophosphamide,
pubmed-meshheading:14960654-Feasibility Studies,
pubmed-meshheading:14960654-Liver Neoplasms, Experimental,
pubmed-meshheading:14960654-Male,
pubmed-meshheading:14960654-Organotechnetium Compounds,
pubmed-meshheading:14960654-Rats,
pubmed-meshheading:14960654-Rats, Wistar,
pubmed-meshheading:14960654-Time Factors,
pubmed-meshheading:14960654-Tissue Distribution
|
pubmed:year |
2004
|
pubmed:articleTitle |
Feasibility of 99mTc-annexin V for repetitive detection of apoptotic tumor response to chemotherapy: an experimental study using a rat tumor model.
|
pubmed:affiliation |
Department of Tracer Kinetics, Graduate School of Medicine, Hokkaido University, Kita15 Nishi7, Kita-ku, Sapporo 060-8638, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|