rdf:type |
|
lifeskim:mentions |
umls-concept:C0001675,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0035696,
umls-concept:C0040648,
umls-concept:C0058697,
umls-concept:C0080138,
umls-concept:C0162788,
umls-concept:C0205266,
umls-concept:C0231491,
umls-concept:C0441889,
umls-concept:C0547047,
umls-concept:C1414314,
umls-concept:C2603343
|
pubmed:issue |
2
|
pubmed:dateCreated |
1993-3-2
|
pubmed:abstractText |
By in situ hybridization with an oligonucleotide probe, we have studied the cellular distribution of the messenger RNA encoding the transcription factor zif268 (krox-24) in the adult intact rat striatum and regulation of its synthesis by acute treatment with the dopamine D1 receptor antagonist SCH-23390. Zif268 mRNA was found in the striatal medium-sized neurons and not in the large cells. Its levels were decreased by SCH-23390, suggesting activation of this immediate early gene in the striatum through dopamine D1 receptor stimulation.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0304-3940
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
7
|
pubmed:volume |
147
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
182-4
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:1491805-Animals,
pubmed-meshheading:1491805-Benzazepines,
pubmed-meshheading:1491805-Corpus Striatum,
pubmed-meshheading:1491805-DNA Probes,
pubmed-meshheading:1491805-In Situ Hybridization,
pubmed-meshheading:1491805-Male,
pubmed-meshheading:1491805-RNA, Messenger,
pubmed-meshheading:1491805-Rats,
pubmed-meshheading:1491805-Rats, Wistar,
pubmed-meshheading:1491805-Receptors, Dopamine D1,
pubmed-meshheading:1491805-Transcription Factors
|
pubmed:year |
1992
|
pubmed:articleTitle |
The dopamine D1 receptor antagonist SCH-23390 decreases the mRNA levels of the transcription factor zif268 (krox-24) in adult rat intact striatum--an in situ hybridization study.
|
pubmed:affiliation |
Laboratory of Neurophysiology, Université Libre de Bruxelles, Belgium.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|