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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1993-2-25
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pubmed:abstractText |
IgA antigliadin antibodies (IgA-AGA) have been determined with an enzyme immunoassay in 2.141 pediatric patients. High levels of IgA were found in 98% of 53 celiac patients (1st biopsy), in 81% of 16 celiac patients after gluten challenge, while high levels of these antibodies were not found in 200 patients on gluten-free diet. Moreover high levels of IgA-AGA were found in 29% of 48 patients with normal jejunal biopsy and in 4% of 1.824 patients with gastrointestinal problems other than celiac disease. Our results confirm the data report in literature about the sensibility and the specificity of the IgA-AGA dosage as a screening test for celiac disease, but the possibility of false pathological and false normal values confirms the intestinal biopsy, as the main procedure for the diagnosis of celiac disease.
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pubmed:language |
ita
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0391-5387
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
N
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pubmed:pagination |
517-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1488309-Antibodies,
pubmed-meshheading:1488309-Celiac Disease,
pubmed-meshheading:1488309-Child,
pubmed-meshheading:1488309-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:1488309-Follow-Up Studies,
pubmed-meshheading:1488309-Gliadin,
pubmed-meshheading:1488309-Humans,
pubmed-meshheading:1488309-Immunoglobulin A,
pubmed-meshheading:1488309-Sensitivity and Specificity
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pubmed:articleTitle |
[IgA-class antigliadin antibodies in the screening and follow-up of celiac disease patients].
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pubmed:affiliation |
Divisione di Gastroenterologia, Ospedale Bambino Gesù, Roma, Italia.
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract,
Research Support, Non-U.S. Gov't
|