rdf:type |
|
lifeskim:mentions |
umls-concept:C0005767,
umls-concept:C0008976,
umls-concept:C0010592,
umls-concept:C0022671,
umls-concept:C0035015,
umls-concept:C0205164,
umls-concept:C0233820,
umls-concept:C0441889,
umls-concept:C0543467,
umls-concept:C1521761,
umls-concept:C1548437,
umls-concept:C1551336,
umls-concept:C1882923,
umls-concept:C1883708
|
pubmed:issue |
3
|
pubmed:dateCreated |
2004-2-11
|
pubmed:abstractText |
Target organs express antigens recognized directly by antigen-specific T cells, and their recognition is crucial to precipitate rejection. Then, the earliest T-cell activation is inhibited by cyclosporine A (CsA), the lowest would be the risk of rejection. Here, we aimed to assess this possibility in a large cohort of de novo kidney transplant recipients participating in an ongoing clinical trial, the Mycophenolate Steroid-Sparing (MY.S.S.) Trial.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0085-2538
|
pubmed:author |
pubmed-author:DimitrovBorislav DBD,
pubmed-author:EOO,
pubmed-author:GanevaMariaM,
pubmed-author:GaspariFlavioF,
pubmed-author:GottiElianaE,
pubmed-author:JazínE EEE,
pubmed-author:MY.S.S. Study Investigators,
pubmed-author:PericoNorbertoN,
pubmed-author:RemuzziGiuseppeG,
pubmed-author:RuggenentiPieroP,
pubmed-author:SalvadoriMaurizioM,
pubmed-author:SandriniSilvioS,
pubmed-author:SegoloniGiuseppeG,
pubmed-author:ValenteUmbertoU
|
pubmed:issnType |
Print
|
pubmed:volume |
65
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1084-90
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:14871429-Acute Disease,
pubmed-meshheading:14871429-Adolescent,
pubmed-meshheading:14871429-Adult,
pubmed-meshheading:14871429-Aged,
pubmed-meshheading:14871429-Cyclosporine,
pubmed-meshheading:14871429-Female,
pubmed-meshheading:14871429-Follow-Up Studies,
pubmed-meshheading:14871429-Graft Rejection,
pubmed-meshheading:14871429-Humans,
pubmed-meshheading:14871429-Immunosuppressive Agents,
pubmed-meshheading:14871429-Kidney Transplantation,
pubmed-meshheading:14871429-Male,
pubmed-meshheading:14871429-Middle Aged,
pubmed-meshheading:14871429-Predictive Value of Tests,
pubmed-meshheading:14871429-Prospective Studies
|
pubmed:year |
2004
|
pubmed:articleTitle |
In renal transplantation blood cyclosporine levels soon after surgery act as a major determinant of rejection: insights from the MY.S.S. trial.
|
pubmed:affiliation |
Department of Medicine and Transplantation, Azienda Ospedaliera, Ospedali Riuniti di Bergamo-Mario Negri Institute for Pharmacological Research, Bergamo, Italy.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|