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pubmed-article:1483116pubmed:abstractTextIn this work the authors studied the effects of interleukin-1 alpha on metabolic activities of human osteoblast-like cells in vitro. The bone nature of the cells was established by assaying for specific bone protein, the osteonectin, and the parathormone receptor, an osteoblast marker. Administration of interleukin-1 alpha to cultured osteoblasts produce an increase in cellular proliferation as suggested by 3H-thymidine incorporation and cell growth studies. Interleukin-1 alpha also affected collagen synthesis confirming its potential role on bone-formation and resorption processes.lld:pubmed
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pubmed-article:1483116pubmed:articleTitleInterleukin-1 alpha: regulation of cellular proliferation and collagen synthesis in cultured human osteoblast-like cells.lld:pubmed
pubmed-article:1483116pubmed:affiliationDipartimento di Medicina Sperimentale e Scienze Biochimiche, Università degli Studi Perugia, Italie.lld:pubmed
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pubmed-article:1483116pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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