pubmed-article:14766874 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:14766874 | lifeskim:mentions | umls-concept:C0042776 | lld:lifeskim |
pubmed-article:14766874 | lifeskim:mentions | umls-concept:C0021311 | lld:lifeskim |
pubmed-article:14766874 | lifeskim:mentions | umls-concept:C0521026 | lld:lifeskim |
pubmed-article:14766874 | lifeskim:mentions | umls-concept:C0026882 | lld:lifeskim |
pubmed-article:14766874 | lifeskim:mentions | umls-concept:C0457454 | lld:lifeskim |
pubmed-article:14766874 | lifeskim:mentions | umls-concept:C0206243 | lld:lifeskim |
pubmed-article:14766874 | lifeskim:mentions | umls-concept:C1963724 | lld:lifeskim |
pubmed-article:14766874 | lifeskim:mentions | umls-concept:C1444662 | lld:lifeskim |
pubmed-article:14766874 | lifeskim:mentions | umls-concept:C0868928 | lld:lifeskim |
pubmed-article:14766874 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:14766874 | pubmed:dateCreated | 2004-2-9 | lld:pubmed |
pubmed-article:14766874 | pubmed:abstractText | A total of 76 patients discontinued treatment with didanosine plus hydroxyurea after 1 year of maintenance therapy. The greatest human immunodeficiency virus (HIV)-RNA rebounds were seen in 10 patients harboring an L74V mutation, and the presence of viruses with this mutation rapidly waned. In contrast, viral rebounds were significantly less pronounced (P < 0.01) in 12 subjects harboring thymidine-associated mutations; these mutations persisted in all instances. Thus, selection of an L74V mutation during didanosine therapy may compromise HIV replication in vivo. | lld:pubmed |
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pubmed-article:14766874 | pubmed:language | eng | lld:pubmed |
pubmed-article:14766874 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:14766874 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:14766874 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:14766874 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:14766874 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:14766874 | pubmed:month | Feb | lld:pubmed |
pubmed-article:14766874 | pubmed:issn | 0095-1137 | lld:pubmed |
pubmed-article:14766874 | pubmed:author | pubmed-author:BarreiroPablo... | lld:pubmed |
pubmed-article:14766874 | pubmed:author | pubmed-author:SorianoVincen... | lld:pubmed |
pubmed-article:14766874 | pubmed:author | pubmed-author:NúñezMarinaM | lld:pubmed |
pubmed-article:14766874 | pubmed:author | pubmed-author:de... | lld:pubmed |
pubmed-article:14766874 | pubmed:author | pubmed-author:PaxinosEllenE | lld:pubmed |
pubmed-article:14766874 | pubmed:author | pubmed-author:CaminoNuriaN | lld:pubmed |
pubmed-article:14766874 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:14766874 | pubmed:volume | 42 | lld:pubmed |
pubmed-article:14766874 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:14766874 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:14766874 | pubmed:pagination | 862-6 | lld:pubmed |
pubmed-article:14766874 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:14766874 | pubmed:year | 2004 | lld:pubmed |
pubmed-article:14766874 | pubmed:articleTitle | Different viral rebound following discontinuation of antiretroviral therapy in cases of infection with viruses carrying L74V or thymidine-associated mutations. | lld:pubmed |
pubmed-article:14766874 | pubmed:affiliation | Service of Infectious Diseases, Hospital Carlos III, Madrid, Spain. | lld:pubmed |
pubmed-article:14766874 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:14766874 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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