Source:http://linkedlifedata.com/resource/pubmed/id/14762681
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2004-2-5
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pubmed:abstractText |
PATIENT: We report on an unusual case of a recurrent and progressive spinal pilocytic astrocytoma with metastatic spreading to the hypothalamus in a 14-year-old boy. TREATMENT AND RESULTS: The patient underwent resection of an intramedullary atypical pilocytic astrocytoma classified as WHO grade II at the level of Th11/12 in 1997 and received local photon beam irradiation. Three years later, a second operation was necessary for a recurrent tumour at the same level. Seventeen months later, a second recurrent tumour with spinal seeding as well as an intracranial tumour in the third ventricle and hypothalamus was detected. He was shunted for an occlusive hydrocephalus and a stereotactic biopsy of the hypothalamic lesion was performed. The tumour was classified as anaplastic pilocytic astrocytoma (WHO grade III). He received chemotherapy with ifosfamide, cisplatin and etoposide (HIT-GBM-C-protocol), craniospinal radiation, and is still alive 60 months after the first operative intervention without neurological deficits.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0256-7040
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
114-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:14762681-Adolescent,
pubmed-meshheading:14762681-Astrocytoma,
pubmed-meshheading:14762681-Brain,
pubmed-meshheading:14762681-Cerebral Ventricle Neoplasms,
pubmed-meshheading:14762681-Combined Modality Therapy,
pubmed-meshheading:14762681-Humans,
pubmed-meshheading:14762681-Hypothalamic Neoplasms,
pubmed-meshheading:14762681-Magnetic Resonance Imaging,
pubmed-meshheading:14762681-Male,
pubmed-meshheading:14762681-Spinal Cord Neoplasms,
pubmed-meshheading:14762681-Tomography, X-Ray Computed
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pubmed:year |
2004
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pubmed:articleTitle |
Recurrent spinal cord astrocytoma with intraventricular seeding.
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pubmed:affiliation |
Department of Neurosurgery, Ludwig-Maximilians-University, Marchioninistrasse 15, 81377 Munich, Germany.
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pubmed:publicationType |
Journal Article,
Case Reports
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