rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2004-1-28
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pubmed:abstractText |
Gliomas are the most common primary tumours of the central nervous system and exhibit rapid growth that is associated with neovascularisation. Adrenomedullin is an important tumour survival factor in human carcinogenesis. It has growth promoting effects on gliomas, and blockade of its actions has been experimentally shown to reduce the growth of glioma tissues and cell lines. There is some evidence that the calcitonin receptor-like receptor (CRLR) mediates the tumorigenic actions of adrenomedullin. Aim: To determine whether CRLR is expressed in human gliomas and the probable cellular targets of adrenomedullin.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0021-9746
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
172-6
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:14747444-Calcitonin Receptor-Like Protein,
pubmed-meshheading:14747444-Endothelium, Vascular,
pubmed-meshheading:14747444-Glioma,
pubmed-meshheading:14747444-Humans,
pubmed-meshheading:14747444-Immunoenzyme Techniques,
pubmed-meshheading:14747444-Neoplasm Proteins,
pubmed-meshheading:14747444-Neovascularization, Pathologic,
pubmed-meshheading:14747444-Receptors, Calcitonin
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pubmed:year |
2004
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pubmed:articleTitle |
The immunohistochemical expression of calcitonin receptor-like receptor (CRLR) in human gliomas.
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pubmed:affiliation |
Department of Neurosurgery, Philipps-University Marburg, D-35043 Marburg, Germany. benes@med.uni-marburg.de
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pubmed:publicationType |
Journal Article
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