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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1978-5-8
|
| pubmed:abstractText |
The dynamics of pulmonary changes produced by a prolonged daily administration of 1 g per cent solution of BeSO4 in aerosols was pursued by current histopathological methods in periodically sacrificed rabbits. A progressive constitution of beryliosic granulomas involving intralobular and interlobular areas was observed. The epithelioids and giant cells were present in variable proportions. Concomitantly, a cellular thickening of alveolar walls and perivascular cuffs was noted, as well as an intercellular reticulin fibrillogenesis. The intratracheal three-fold administration of a 0.3 g per cent solution of BeSO4 induced a more rapid formation of berylliosic nodules with the same characters. The relation between the cell accumulation and reticulin fibrillogenesis was morphometrically analysed and statistically verified as pertinent correlated phenomena.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0377-5038
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
24
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
75-9
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading | |
| pubmed:articleTitle |
Experimental aerogenic pulmonary berylliosis in rabbits.
|
| pubmed:publicationType |
Journal Article
|