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pubmed-article:14731133pubmed:abstractTextInterstitial cells of Cajal (ICC) are pacemakers and mediators of neurotransmission in gastroenteric smooth muscles. Interstitial cells of Cajal require cellular signaling via KIT, a receptor tyrosine kinase, for development and maintenance of cellular phenotype. Much of the evidence demonstrating the functions of ICC comes from studies of W/W V mutant mice, which have reduced KIT function. The aim of the present study was to differentially examine gene expression in the small intestines of wild-type and W/W V mice.lld:pubmed
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pubmed-article:14731133pubmed:articleTitleNovel human, mouse and xenopus genes encoding a member of the RAS superfamily of low-molecular-weight GTP-binding proteins and its downregulation in W/WV mouse jejunum.lld:pubmed
pubmed-article:14731133pubmed:affiliationDepartment of Medicine, University of Yamanashi School of Medicine, Yamanashi, Japan.lld:pubmed
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pubmed-article:14731133pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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