Source:http://linkedlifedata.com/resource/pubmed/id/14702922
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
46
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pubmed:dateCreated |
2004-1-1
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pubmed:abstractText |
Positron emission tomography (PET) is a useful tool for the investigation of certain physiological changes and for the evaluation of the distribution, and receptor binding of drugs labelled with positron emitting isotopes. Vinpocetine (ethyl-apovincaminate) is a neuroprotective drug widely used in the prevention and treatment of cerebrovascular diseases. In the clinical practice vinpocetine is usually administered to the patients in intravenous infusion followed by long-term oral treatment. Until presently human data describing vinpocetine's kinetics and brain distribution came from ex vivo (blood, plasma, liquor) and post mortem (brain autoradiography) measurements.
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pubmed:language |
hun
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0030-6002
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
16
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pubmed:volume |
144
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2271-6
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pubmed:dateRevised |
2009-10-21
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pubmed:meshHeading |
pubmed-meshheading:14702922-Administration, Oral,
pubmed-meshheading:14702922-Adult,
pubmed-meshheading:14702922-Brain,
pubmed-meshheading:14702922-Carbon Radioisotopes,
pubmed-meshheading:14702922-Humans,
pubmed-meshheading:14702922-Kidney,
pubmed-meshheading:14702922-Liver,
pubmed-meshheading:14702922-Male,
pubmed-meshheading:14702922-Neuroprotective Agents,
pubmed-meshheading:14702922-Reference Values,
pubmed-meshheading:14702922-Stomach,
pubmed-meshheading:14702922-Time Factors,
pubmed-meshheading:14702922-Tissue Distribution,
pubmed-meshheading:14702922-Tomography, Emission-Computed,
pubmed-meshheading:14702922-Vinca Alkaloids
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pubmed:year |
2003
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pubmed:articleTitle |
[Human positron emission tomography with oral 11C-vinpocetine].
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pubmed:affiliation |
Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institute, Stockholm.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
English Abstract
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