| pubmed-article:14698167 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:14698167 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
| pubmed-article:14698167 | lifeskim:mentions | umls-concept:C0878773 | lld:lifeskim |
| pubmed-article:14698167 | lifeskim:mentions | umls-concept:C1955862 | lld:lifeskim |
| pubmed-article:14698167 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:14698167 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:14698167 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:14698167 | lifeskim:mentions | umls-concept:C1707689 | lld:lifeskim |
| pubmed-article:14698167 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:14698167 | lifeskim:mentions | umls-concept:C0057888 | lld:lifeskim |
| pubmed-article:14698167 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:14698167 | pubmed:dateCreated | 2003-12-30 | lld:pubmed |
| pubmed-article:14698167 | pubmed:abstractText | Thiourea derivatives were identified as glyburide-reversible potassium channel openers through high-throughput screening. Based on these findings, a number of novel cyanoguanidines were designed and synthesized, which hyperpolarized human bladder K(ATP) channels. These agents are potent full agonists in relaxing electrically-stimulated pig bladder strips. The synthesis, SAR and biological properties of these agents are discussed. | lld:pubmed |
| pubmed-article:14698167 | pubmed:language | eng | lld:pubmed |
| pubmed-article:14698167 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14698167 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:14698167 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14698167 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14698167 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14698167 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:14698167 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:14698167 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:14698167 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:14698167 | pubmed:author | pubmed-author:BucknerSteven... | lld:pubmed |
| pubmed-article:14698167 | pubmed:author | pubmed-author:CoghlanMichae... | lld:pubmed |
| pubmed-article:14698167 | pubmed:author | pubmed-author:Gopalakrishna... | lld:pubmed |
| pubmed-article:14698167 | pubmed:author | pubmed-author:WhiteakerKris... | lld:pubmed |
| pubmed-article:14698167 | pubmed:author | pubmed-author:SullivanJames... | lld:pubmed |
| pubmed-article:14698167 | pubmed:author | pubmed-author:CarrollWillia... | lld:pubmed |
| pubmed-article:14698167 | pubmed:author | pubmed-author:ScottVictoria... | lld:pubmed |
| pubmed-article:14698167 | pubmed:author | pubmed-author:KortMichael... | lld:pubmed |
| pubmed-article:14698167 | pubmed:author | pubmed-author:Perez-Medrano... | lld:pubmed |
| pubmed-article:14698167 | pubmed:author | pubmed-author:GreggRobert... | lld:pubmed |
| pubmed-article:14698167 | pubmed:author | pubmed-author:LynchJohn KJK | lld:pubmed |
| pubmed-article:14698167 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:14698167 | pubmed:day | 19 | lld:pubmed |
| pubmed-article:14698167 | pubmed:volume | 14 | lld:pubmed |
| pubmed-article:14698167 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:14698167 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:14698167 | pubmed:pagination | 397-400 | lld:pubmed |
| pubmed-article:14698167 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:14698167 | pubmed:meshHeading | pubmed-meshheading:14698167... | lld:pubmed |
| pubmed-article:14698167 | pubmed:meshHeading | pubmed-meshheading:14698167... | lld:pubmed |
| pubmed-article:14698167 | pubmed:meshHeading | pubmed-meshheading:14698167... | lld:pubmed |
| pubmed-article:14698167 | pubmed:meshHeading | pubmed-meshheading:14698167... | lld:pubmed |
| pubmed-article:14698167 | pubmed:meshHeading | pubmed-meshheading:14698167... | lld:pubmed |
| pubmed-article:14698167 | pubmed:meshHeading | pubmed-meshheading:14698167... | lld:pubmed |
| pubmed-article:14698167 | pubmed:meshHeading | pubmed-meshheading:14698167... | lld:pubmed |
| pubmed-article:14698167 | pubmed:meshHeading | pubmed-meshheading:14698167... | lld:pubmed |
| pubmed-article:14698167 | pubmed:meshHeading | pubmed-meshheading:14698167... | lld:pubmed |
| pubmed-article:14698167 | pubmed:meshHeading | pubmed-meshheading:14698167... | lld:pubmed |
| pubmed-article:14698167 | pubmed:year | 2004 | lld:pubmed |
| pubmed-article:14698167 | pubmed:articleTitle | Design and synthesis of novel cyanoguanidine ATP-sensitive potassium channel openers for the treatment of overactive bladder. | lld:pubmed |
| pubmed-article:14698167 | pubmed:affiliation | Abbott Laboratories, Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Park, IL 60064, USA. arturo.perezmedrano@abbott.com | lld:pubmed |
| pubmed-article:14698167 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:14698167 | pubmed:publicationType | In Vitro | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:14698167 | lld:chembl |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:14698167 | lld:pubmed |
