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rdf:type |
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lifeskim:mentions |
umls-concept:C0013081,
umls-concept:C0017347,
umls-concept:C0021853,
umls-concept:C0205197,
umls-concept:C0300483,
umls-concept:C0334037,
umls-concept:C0449258,
umls-concept:C1332743,
umls-concept:C1413301,
umls-concept:C1512167,
umls-concept:C1704242,
umls-concept:C1707520
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pubmed:issue |
3
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pubmed:dateCreated |
2004-9-27
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pubmed:abstractText |
The molecular mechanisms underlying the development of intestinal metaplasia (IM) of the human stomach have yet to be clarified in detail. Besides ectopic expression of intestinal transcription factors, Cdx1 and Cdx2, little information is available regarding other regulatory factors. Hence, we here analyzed Sox2, a human homolog of a chicken gastric transcription factor, with reference to our new classification for gastric/intestinal (GI)-mixed type IM.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Avian Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Concanavalin A,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/HMGB Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Homeodomain Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/MUC5AC protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/MUC5B protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/MUC6 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Mucin 5AC,
http://linkedlifedata.com/resource/pubmed/chemical/Mucin-5B,
http://linkedlifedata.com/resource/pubmed/chemical/Mucin-6,
http://linkedlifedata.com/resource/pubmed/chemical/Mucins,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/SOX2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/SOXB1 Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0171-5216
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
130
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
135-45
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:14655050-Avian Proteins,
pubmed-meshheading:14655050-Concanavalin A,
pubmed-meshheading:14655050-DNA-Binding Proteins,
pubmed-meshheading:14655050-Disease Progression,
pubmed-meshheading:14655050-Down-Regulation,
pubmed-meshheading:14655050-Gastric Mucosa,
pubmed-meshheading:14655050-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:14655050-HMGB Proteins,
pubmed-meshheading:14655050-Homeodomain Proteins,
pubmed-meshheading:14655050-Humans,
pubmed-meshheading:14655050-Immunoenzyme Techniques,
pubmed-meshheading:14655050-Intestinal Mucosa,
pubmed-meshheading:14655050-Metaplasia,
pubmed-meshheading:14655050-Mucin 5AC,
pubmed-meshheading:14655050-Mucin-5B,
pubmed-meshheading:14655050-Mucin-6,
pubmed-meshheading:14655050-Mucins,
pubmed-meshheading:14655050-Nuclear Proteins,
pubmed-meshheading:14655050-RNA, Messenger,
pubmed-meshheading:14655050-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:14655050-SOXB1 Transcription Factors,
pubmed-meshheading:14655050-Stomach Neoplasms,
pubmed-meshheading:14655050-Transcription Factors
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pubmed:year |
2004
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pubmed:articleTitle |
Down-regulation of a gastric transcription factor, Sox2, and ectopic expression of intestinal homeobox genes, Cdx1 and Cdx2: inverse correlation during progression from gastric/intestinal-mixed to complete intestinal metaplasia.
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pubmed:affiliation |
Division of Oncological Pathology, Aichi Cancer Center Research Institute, 1-1 Kanokoden, Nagoya, Chikusa-ku, Japan. ttsukamt@aichi-cc.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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