14651860

Source:http://linkedlifedata.com/resource/pubmed/id/14651860

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0004611, umls-concept:C0042765, umls-concept:C0162340, umls-concept:C1002020, umls-concept:C1722730
pubmed:issue	2-3
pubmed:dateCreated	2003-12-3
pubmed:abstractText	Clavibacter michiganensis subsp. michiganensis is a plant-pathogenic actinomycete. It infects tomato, spreads through the xylem and causes bacterial wilt and canker. The wild-type strain NCPPB382 carries two plasmids, pCM1 and pCM2. The cured plasmid-free derivative CMM100 is still able to colonize tomato, but no disease symptoms develop indicating that all genes required for successful infection, establishment and growth in the plant reside on the chromosome. Both plasmids carry one virulence factor, a gene encoding a cellulase, CelA in case of pCM1 and a putative serine protease Pat-1 on pCM2. These genes can independently convert the non-virulent strain CMM100 into a pathogen causing wilt on tomatoes. Currently, genome projects for Cmm and the closely related potato-pathogen C. michiganensis subsp. sepedonicus have been initiated. The data from the genome project shall give clues on further genes involved in plant-microbe interaction that can be tested experimentally. Especially, identification of genes related to host-specificity through genome comparison of the two subspecies might be possible.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8411927
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Dec
pubmed:issn	0168-1656
pubmed:author	pubmed-author:BurgerAnnetteA, pubmed-author:EichenlaubRudolfR, pubmed-author:EngemannJuttaJ, pubmed-author:GartemannKarl-HeinzKH, pubmed-author:GräfenInesI, pubmed-author:KirchnerOliverO
pubmed:issnType	Print
pubmed:day	19
pubmed:volume	106
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	179-91
pubmed:dateRevised	2005-11-16
pubmed:meshHeading	pubmed-meshheading:14651860-Actinomycetales, pubmed-meshheading:14651860-Gene Expression Regulation, Bacterial, pubmed-meshheading:14651860-Gram-Positive Bacteria, pubmed-meshheading:14651860-Lycopersicon esculentum, pubmed-meshheading:14651860-Plant Diseases, pubmed-meshheading:14651860-Species Specificity
pubmed:year	2003
pubmed:articleTitle	Clavibacter michiganensis subsp. michiganensis: first steps in the understanding of virulence of a Gram-positive phytopathogenic bacterium.
pubmed:affiliation	Lehrstuhl Gentechnologie/Mikrobiologie, Fakultät für Biologie, Universität Bielefeld, Universitätsstrasse 25, D-33501 Bielefeld, Germany.
pubmed:publicationType	Journal Article, Review