Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2003-12-3
pubmed:abstractText
Intervention for valvular heart disease poses unique clinical challenges in cardiology because the diseases are of relatively low prevalence, the interventions do not lend themselves to randomized comparative trials, and important clinical end points are assessed only after decades of follow-up. In addition, continuing advances in prosthetic heart valve technology make follow-up a moving target because long-term data by definition are available only for older prostheses. Newer tissue and mechanical prostheses afford superior hemodynamics compared with their older counterparts, and data suggest that durability and patient mortality are superior with newer compared with older bioprostheses. Arbitrary cutoffs dictating valve choice based predominantly on patient age may not give appropriate weight to individual patient perspectives. In educating and counseling patients regarding choices in heart valve prostheses, the clinician should help the patient weigh the relative merits for the individual patient of projected mortality, valve durability, and requirement for anticoagulation, with associated freedom from re-operation, hemorrhagic and thromboembolic risk, and impact on lifestyle.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0735-1097
pubmed:author
pubmed:issnType
Print
pubmed:day
19
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1717-9
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Choice of prosthetic heart valves:update for the next generation.
pubmed:affiliation
Department of Medicine, Division of Cardiology, University of Michigan, Ann Arbor, Michigan 48109-0273, USA. dbach@umich.edu
pubmed:publicationType
Journal Article, Comment