Source:http://linkedlifedata.com/resource/pubmed/id/14636901
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2003-11-25
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pubmed:abstractText |
Patients with normal dobutamine stress echocardiography (DSE) were shown to have a favorable outcome at an intermediate-term follow-up. However, there are scarce data regarding long-term survival after normal DSE. This study sought to assess the long-term outcome after normal DSE. We studied 401 patients (age 62 +/- 10 years, 264 men) who had a normal echocardiogram at rest and with high-dose dobutamine stress. End points during a mean follow-up of 5 +/- 1.7 years (minimum 3.5) were all-cause mortality and hard cardiac events (cardiac death and nonfatal myocardial infarction). During follow-up, 45 patients (11%) died due to various causes (cardiac death in 10 patients). Thirteen patients had nonfatal myocardial infarction (a total of 23 hard cardiac events). The annual mortality rate was 2% in the first 3 years and 2.4% between the fourth and sixth years. The annual hard cardiac event rate was 0.8% in the first 3 years and 1.7% between the fourth and sixth years. Predictors of mortality in a multivariate analysis model were advanced age (hazard ratio 1.2, 95% confidence interval CI 1.1 to 1.4) and higher heart rate at rest (hazard ratio 0.92, 95% confidence interval 0.85 to 0.99). Patients with normal DSE had excellent outcomes during the 3 years after the study. The cardiac event rate was higher between the fourth and sixth year; therefore, it may be useful to repeat the study after 3 years to reassess risk status.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0002-9149
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
92
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1267-70
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:14636901-Cardiotonic Agents,
pubmed-meshheading:14636901-Chi-Square Distribution,
pubmed-meshheading:14636901-Coronary Disease,
pubmed-meshheading:14636901-Dobutamine,
pubmed-meshheading:14636901-Echocardiography,
pubmed-meshheading:14636901-Female,
pubmed-meshheading:14636901-Follow-Up Studies,
pubmed-meshheading:14636901-Humans,
pubmed-meshheading:14636901-Male,
pubmed-meshheading:14636901-Middle Aged,
pubmed-meshheading:14636901-Prognosis,
pubmed-meshheading:14636901-Proportional Hazards Models,
pubmed-meshheading:14636901-Statistics, Nonparametric,
pubmed-meshheading:14636901-Survival Rate
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pubmed:year |
2003
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pubmed:articleTitle |
Long-term prognosis after normal dobutamine stress echocardiography.
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pubmed:affiliation |
Department of Cardiology, IRCCS, Ospedale Maggiore, Milan, Italy.
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pubmed:publicationType |
Journal Article
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