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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2004-2-13
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pubmed:abstractText |
Fas-mediated apoptosis is preferentially observed in synoviocytes of patients with rheumatoid arthritis (RA) and is associated with the pathophysiological process of RA. To clarify the molecular mechanisms of Fas-mediated apoptosis of RA synoviocytes, we investigated the role of the mitochondrial pathway and tumour suppressor p53 in this process.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1462-0324
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
277-85
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pubmed:dateRevised |
2007-9-6
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pubmed:meshHeading |
pubmed-meshheading:14623946-Antigens, CD95,
pubmed-meshheading:14623946-Apoptosis,
pubmed-meshheading:14623946-Arthritis, Rheumatoid,
pubmed-meshheading:14623946-Cells, Cultured,
pubmed-meshheading:14623946-Humans,
pubmed-meshheading:14623946-Membrane Potentials,
pubmed-meshheading:14623946-Mitochondria,
pubmed-meshheading:14623946-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:14623946-Synovial Membrane,
pubmed-meshheading:14623946-Tumor Suppressor Protein p53
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pubmed:year |
2004
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pubmed:articleTitle |
Central role of mitochondria and p53 in Fas-mediated apoptosis of rheumatoid synovial fibroblasts.
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pubmed:affiliation |
Division of Immunology, Institute for Medical Science, Dokkyo University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi 321-0293, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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