Source:http://linkedlifedata.com/resource/pubmed/id/14605617
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
2003-11-7
|
pubmed:abstractText |
Secretory immunoglobulin A (SIgA) is the principal immune defense against luminal pathogens at gut mucosal surfaces. It also has anti-inflammatory activities that may be important for the maintenance of mucosal surface integrity. Enterocyte apoptosis (Apo) is increased after challenge with invasive bacteria and ischemia-reperfusion insults. Increased Apo also has been associated with impaired intestinal barrier function. However, the impact of SIgA on enterocyte apoptosis and mucosal barrier integrity after challenge with commensal bacteria and ischemia-reperfusion is unknown.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0039-6060
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
134
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
574-80; discussion 580-1
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:14605617-Apoptosis,
pubmed-meshheading:14605617-Caco-2 Cells,
pubmed-meshheading:14605617-Cell Hypoxia,
pubmed-meshheading:14605617-Cell Membrane Permeability,
pubmed-meshheading:14605617-Enterocytes,
pubmed-meshheading:14605617-Escherichia coli Infections,
pubmed-meshheading:14605617-Humans,
pubmed-meshheading:14605617-Immunoglobulin A, Secretory,
pubmed-meshheading:14605617-Oxygen
|
pubmed:year |
2003
|
pubmed:articleTitle |
Enterocyte apoptosis and barrier function are modulated by SIgA after exposure to bacteria and hypoxia/reoxygenation.
|
pubmed:affiliation |
University Health Center 6-C, Wayne State University, 4201 St. Antoine, Detroit, MI 48201, USA.
|
pubmed:publicationType |
Journal Article
|