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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2003-10-21
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pubmed:abstractText |
The stereochemistry of prunioside A isolated from Spiraea prunifolia was determined by chemical transformations and NMR spectral data analysis. The configurations at C-5 and C-6 were determined to be 5S and 6R by application of the modified Mosher's method, CD analysis, and 13C NMR spectroscopic data analysis of an acetonide derivative. Other compounds related to prunioside A have inhibitory effects on the synthesis of nitric oxide in LPS-stimulated macrophage-like RAW 264.7 cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0031-9422
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1113-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14568077-Animals,
pubmed-meshheading:14568077-Cell Line,
pubmed-meshheading:14568077-Dose-Response Relationship, Drug,
pubmed-meshheading:14568077-Glycosides,
pubmed-meshheading:14568077-Macrophages,
pubmed-meshheading:14568077-Magnetic Resonance Spectroscopy,
pubmed-meshheading:14568077-Mice,
pubmed-meshheading:14568077-Molecular Conformation,
pubmed-meshheading:14568077-Nitric Oxide,
pubmed-meshheading:14568077-Nitric Oxide Synthase,
pubmed-meshheading:14568077-Nitric Oxide Synthase Type II,
pubmed-meshheading:14568077-Spiraea,
pubmed-meshheading:14568077-Stereoisomerism,
pubmed-meshheading:14568077-Terpenes
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pubmed:year |
2003
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pubmed:articleTitle |
The absolute configuration of prunioside A from Spiraea prunifolia and biological activities of related compounds.
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pubmed:affiliation |
Professional Graduate School of Oriental Medicine, Wonkwang University, Iksan, Chonbuk 570-749, South Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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