Source:http://linkedlifedata.com/resource/pubmed/id/14565386
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5-8
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| pubmed:dateCreated |
2003-10-20
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| pubmed:abstractText |
In an effort to further improve the hybridisation potential of anhydro-hexitol nucleoside analogues, the 1'-methoxyl and 3'-methoxyl substituents were introduced and evaluated for their antisense potential. In view of the selectivity of pairing with RNA, especially the introduction of a 3'-O-alkyl moiety deserves further study.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:issn |
1525-7770
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
22
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1227-9
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| pubmed:meshHeading | |
| pubmed:articleTitle |
Methylated hexitol nucleic acids, towards congeners with improved antisense potential.
|
| pubmed:affiliation |
Laboratory for Medicinal Chemistry, Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, Belgium. arthur.vanaerschot@rega.kuleuven.ac.be
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| pubmed:publicationType |
Journal Article
|