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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
2003-10-15
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pubmed:abstractText |
Ihara epileptic rat (IER) is an animal model of temporal lobe epilepsy (TLE) with genetically programmed microdysgenesis in the hippocampal formation. The neuronal microdysgenesis is thought to be a cause for recurrent spontaneous seizures. To identify differentially expressed genes in the hippocampus of IER in comparison to control Wistar rat, we performed serial analysis of gene expression (SAGE). As many as 21 differentially expressed genes were identified.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0169-328X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
21
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pubmed:volume |
118
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
147-51
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14559364-Animals,
pubmed-meshheading:14559364-DNA Fingerprinting,
pubmed-meshheading:14559364-Disease Models, Animal,
pubmed-meshheading:14559364-Down-Regulation,
pubmed-meshheading:14559364-Epilepsy, Temporal Lobe,
pubmed-meshheading:14559364-Gene Expression Profiling,
pubmed-meshheading:14559364-Gene Expression Regulation, Developmental,
pubmed-meshheading:14559364-Genetic Predisposition to Disease,
pubmed-meshheading:14559364-Hippocampus,
pubmed-meshheading:14559364-Male,
pubmed-meshheading:14559364-Nerve Tissue Proteins,
pubmed-meshheading:14559364-Nervous System Malformations,
pubmed-meshheading:14559364-Neurons,
pubmed-meshheading:14559364-RNA, Messenger,
pubmed-meshheading:14559364-Rats,
pubmed-meshheading:14559364-Rats, Mutant Strains,
pubmed-meshheading:14559364-Up-Regulation
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pubmed:year |
2003
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pubmed:articleTitle |
Identification of epilepsy-related genes by gene expression profiling in the hippocampus of genetically epileptic rat.
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pubmed:affiliation |
Department of Biochemistry II, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-0042, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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