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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2003-10-14
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pubmed:abstractText |
Membrane-associated prostaglandin E synthase (mPGES) is a recently identified terminal enzyme of the arachidonic acid cascade, which converts PGH(2) to PGE(2) in rheumatoid arthritis synovial fibroblasts (RASFs). This study was undertaken to investigate factors regulating the expression of mPGES.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Inflammatory Agents...,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic AMP,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclooxygenase 2,
http://linkedlifedata.com/resource/pubmed/chemical/Dinoprostone,
http://linkedlifedata.com/resource/pubmed/chemical/Forskolin,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1,
http://linkedlifedata.com/resource/pubmed/chemical/Intramolecular Oxidoreductases,
http://linkedlifedata.com/resource/pubmed/chemical/Isoenzymes,
http://linkedlifedata.com/resource/pubmed/chemical/Lactones,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/PTGER2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/PTGER4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/PTGS2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Prostaglandin-Endoperoxide Synthases,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Prostaglandin E,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Prostaglandin E, EP2...,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Prostaglandin E, EP4...,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfones,
http://linkedlifedata.com/resource/pubmed/chemical/prostaglandin-E synthase,
http://linkedlifedata.com/resource/pubmed/chemical/rofecoxib
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2819-28
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:14558087-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:14558087-Arthritis, Rheumatoid,
pubmed-meshheading:14558087-Cells, Cultured,
pubmed-meshheading:14558087-Cyclic AMP,
pubmed-meshheading:14558087-Cyclooxygenase 2,
pubmed-meshheading:14558087-Dinoprostone,
pubmed-meshheading:14558087-Fibroblasts,
pubmed-meshheading:14558087-Forskolin,
pubmed-meshheading:14558087-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:14558087-Humans,
pubmed-meshheading:14558087-Interleukin-1,
pubmed-meshheading:14558087-Intramolecular Oxidoreductases,
pubmed-meshheading:14558087-Isoenzymes,
pubmed-meshheading:14558087-Lactones,
pubmed-meshheading:14558087-Membrane Proteins,
pubmed-meshheading:14558087-Prostaglandin-Endoperoxide Synthases,
pubmed-meshheading:14558087-RNA, Messenger,
pubmed-meshheading:14558087-Receptors, Prostaglandin E,
pubmed-meshheading:14558087-Receptors, Prostaglandin E, EP2 Subtype,
pubmed-meshheading:14558087-Receptors, Prostaglandin E, EP4 Subtype,
pubmed-meshheading:14558087-Sulfones,
pubmed-meshheading:14558087-Synovial Membrane
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pubmed:year |
2003
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pubmed:articleTitle |
Prostaglandin E2 is an enhancer of interleukin-1beta-induced expression of membrane-associated prostaglandin E synthase in rheumatoid synovial fibroblasts.
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pubmed:affiliation |
St. Marianna University School of Medicine, Kawasaki, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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