Linezolid is an effective and well-tolerated antibiotic for the treatment of Gram-positive infections, including hospital and community-acquired pneumonia and complicated and uncomplicated skin and skin structure infections. In adults linezolid treatment for >/=2 weeks has been associated with reversible hematopoietic suppression, primarily thrombocytopenia.
Pediatric Infectious Diseases, New England Medical Center, Tufts University School of Medicine, 750 Washington Street, NEMCH Box 321, Boston, MA 02111, USA. CMeissner@tufts-nemc.org