Source:http://linkedlifedata.com/resource/pubmed/id/14520094
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2003-10-1
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pubmed:abstractText |
The auditory efferent system plays presumed roles in enhancing signals in noise, maintaining the cochlea for optimal acoustic signal processing, and may have a protective role in preserving auditory function in the face of ototoxic events. The objective of the study was to measure age-related changes of the medial olivocochlear efferent system in mice by comparing distortion-product otoacoustic emissions generated with and without contralateral white noise stimulation. Consistent with prior work, distortion-product otoacoustic emissions were typically reduced in magnitude when white noise was presented to the contralateral ear. This contralateral suppression is attributed to activation of the medial olivocochlear efferent system, which has an inhibitory effect on the cochlear hair cell system. By studying contralateral suppression on cochlear output in subjects of different ages, it is possible to describe aging effects on the medial olivocochlear system.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0023-852X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
113
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1707-13
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:14520094-Age Factors,
pubmed-meshheading:14520094-Aging,
pubmed-meshheading:14520094-Animals,
pubmed-meshheading:14520094-Cochlea,
pubmed-meshheading:14520094-Evoked Potentials, Auditory, Brain Stem,
pubmed-meshheading:14520094-Female,
pubmed-meshheading:14520094-Male,
pubmed-meshheading:14520094-Mice,
pubmed-meshheading:14520094-Mice, Inbred CBA,
pubmed-meshheading:14520094-Otoacoustic Emissions, Spontaneous,
pubmed-meshheading:14520094-Presbycusis
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pubmed:year |
2003
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pubmed:articleTitle |
Contralateral suppression of distortion-product otoacoustic emissions declines with age: a comparison of findings in CBA mice with human listeners.
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pubmed:affiliation |
Division of Otolaryngology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642-8629, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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