Source:http://linkedlifedata.com/resource/pubmed/id/14516876
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
2003-9-30
|
| pubmed:abstractText |
It has been suggested that early treatment decreases, but late treatment increases, the risk of mechanical complications for a thrombolytic strategy. However, few studies have evaluated whether late reperfusion (LR) by primary coronary angioplasty decreases the risk of mechanical complications. A total of 2,209 patients with acute myocardial infarction treated with primary coronary angioplasty within 24 hours after the onset of symptoms were divided into 3 groups: early reperfusion (ER; < or =12 hours, n = 1,647), LR (>12 hours, n = 219), and failed reperfusion (FR; n = 343). We evaluated the incidence, risk ratio, and predictors of mechanical complications. The overall incidence of mechanical complications was 2.0%. The incidence of mechanical complications was highest in the FR group (ER 1.4%, LR 1.8%, FR 5.0%; p <0.01). After adjusting for clinical variables, the risk ratio for mechanical complications increased in the FR group compared with the LR group (risk ratio 7.34, 95% confidence interval [CI] 1.02 to 52.80; p = 0.04). Predictors of an increased risk of mechanical complications by multivariate analysis were age > or =70 years (odds ratio [OR] 3.68, 95% CI 1.56 to 8.64; p <0.01), Killip class > or =II (OR 3.73, 95% CI 1.53 to 9.12; p <0.01), absence of collateral vessels (OR 4.09, 95% CI 1.17 to 14.26; p = 0.03), and FR (OR 2.68, 95% CI 1.09 to 6.61; p = 0.03). In conclusion, successful LR by primary coronary angioplasty is associated with the reduced risk of mechanical complications in patients with acute myocardial infarction.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0002-9149
|
| pubmed:author |
pubmed-author:HirayamaAtsushiA,
pubmed-author:HishidaEijiE,
pubmed-author:HoriMasatsuguM,
pubmed-author:ItoHiroshiH,
pubmed-author:KinjoKunihiroK,
pubmed-author:MatsumuraYasushiY,
pubmed-author:MishimaMasayoshiM,
pubmed-author:MizunoHiroyaH,
pubmed-author:NakataniDaisakuD,
pubmed-author:Osaka Acute Coronary Insufficiency Study Group,
pubmed-author:SatoHiroshiH
|
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
92
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
785-8
|
| pubmed:dateRevised |
2010-11-18
|
| pubmed:meshHeading |
pubmed-meshheading:14516876-Aged,
pubmed-meshheading:14516876-Angioplasty, Balloon, Coronary,
pubmed-meshheading:14516876-Comorbidity,
pubmed-meshheading:14516876-Coronary Angiography,
pubmed-meshheading:14516876-Female,
pubmed-meshheading:14516876-Heart Rupture, Post-Infarction,
pubmed-meshheading:14516876-Humans,
pubmed-meshheading:14516876-Incidence,
pubmed-meshheading:14516876-Japan,
pubmed-meshheading:14516876-Male,
pubmed-meshheading:14516876-Middle Aged,
pubmed-meshheading:14516876-Mitral Valve Insufficiency,
pubmed-meshheading:14516876-Multivariate Analysis,
pubmed-meshheading:14516876-Myocardial Infarction,
pubmed-meshheading:14516876-Myocardial Reperfusion,
pubmed-meshheading:14516876-Odds Ratio,
pubmed-meshheading:14516876-Time Factors,
pubmed-meshheading:14516876-Treatment Failure,
pubmed-meshheading:14516876-Ventricular Septal Rupture
|
| pubmed:year |
2003
|
| pubmed:articleTitle |
Effect of successful late reperfusion by primary coronary angioplasty on mechanical complications of acute myocardial infarction.
|
| pubmed:affiliation |
Department of Internal Medicine and Therapeutics, Osaka University Graduate School of Medicine, Suita, Japan.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Evaluation Studies
|