Source:http://linkedlifedata.com/resource/pubmed/id/14499871
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2003-9-22
|
| pubmed:abstractText |
Cytosolic calcium ([Ca(2+)](i)) mediates ischemia-reperfusion (I/R) injury, but magnitude and time course of I/R-induced [Ca(2+)](i) overload remain unclear. Fluorescent indicators are commonly used to measure [Ca(2+)](i), and have a dissociation constant (K(d)) that depends on pH and temperature. We hypothesized that changes of K(d) during I/R lead to misleading interpretations of [Ca(2+)](i) recordings.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0008-6363
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
59
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
695-704
|
| pubmed:dateRevised |
2005-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:14499871-Animals,
pubmed-meshheading:14499871-Calcium,
pubmed-meshheading:14499871-Cytosol,
pubmed-meshheading:14499871-Fluorescent Dyes,
pubmed-meshheading:14499871-Heart Arrest, Induced,
pubmed-meshheading:14499871-Heterocyclic Compounds, 3-Ring,
pubmed-meshheading:14499871-Hydrogen-Ion Concentration,
pubmed-meshheading:14499871-Myocardial Ischemia,
pubmed-meshheading:14499871-Perfusion,
pubmed-meshheading:14499871-Rabbits,
pubmed-meshheading:14499871-Spectrometry, Fluorescence
|
| pubmed:year |
2003
|
| pubmed:articleTitle |
Cytosolic calcium in the ischemic rabbit heart: assessment by pH- and temperature-adjusted rhod-2 spectrofluorometry.
|
| pubmed:affiliation |
Universität Rostock, Department of Cardiac Surgery, Schillingallee 35, 18057 Rostock, Germany. christof.stamm@med.uni-rostock.de
|
| pubmed:publicationType |
Journal Article
|