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rdf:type |
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lifeskim:mentions |
umls-concept:C0001675,
umls-concept:C0017262,
umls-concept:C0017968,
umls-concept:C0023688,
umls-concept:C0078058,
umls-concept:C0086418,
umls-concept:C0185117,
umls-concept:C0205263,
umls-concept:C0225828,
umls-concept:C1149423,
umls-concept:C1171892,
umls-concept:C2911684
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pubmed:issue |
3
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pubmed:dateCreated |
2003-9-22
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pubmed:abstractText |
In murine and rat cardiac myocytes the gp130 system transduces survival as well as hypertrophic signals and via induction of the expression of the potent angiogenic factor VEGF in these cells also indirectly contributes to cardiac repair processes through the development of new blood vessels. There are, however, species differences in receptor specificity and receptor crossreactivity in the gp130-gp130 ligand system. We asked whether gp130 signaling is also involved in the regulation of VEGF in human cardiac myocytes and if so which gp130 ligands are critical for such an effect.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Growth Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6,
http://linkedlifedata.com/resource/pubmed/chemical/LIF protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Leukemia Inhibitory Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Lif protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Molecular Chaperones,
http://linkedlifedata.com/resource/pubmed/chemical/OSM protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Oncostatin M,
http://linkedlifedata.com/resource/pubmed/chemical/Organic Cation Transport Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Osm protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/SLC22A5 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Slc22a5 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0008-6363
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pubmed:author |
pubmed-author:BialyJanJ,
pubmed-author:FuernkranzAlexanderA,
pubmed-author:GrantSusan LSL,
pubmed-author:HolzmannPhilippP,
pubmed-author:HuberKurtK,
pubmed-author:KaunChristophC,
pubmed-author:LosertUdo MUM,
pubmed-author:MacfeldaKarinK,
pubmed-author:MarroMartin LML,
pubmed-author:MaurerGeraldG,
pubmed-author:PacherRichardR,
pubmed-author:RegaGersinaG,
pubmed-author:RhodesAndrew DAD,
pubmed-author:SpeidlWalter SWS,
pubmed-author:SpringerChristopherC,
pubmed-author:UllrichRobertR,
pubmed-author:WeissThomas WTW,
pubmed-author:WojtaJohannJ
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
628-38
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:14499864-Adult,
pubmed-meshheading:14499864-Analysis of Variance,
pubmed-meshheading:14499864-Blotting, Western,
pubmed-meshheading:14499864-Carrier Proteins,
pubmed-meshheading:14499864-Cells, Cultured,
pubmed-meshheading:14499864-Glycoproteins,
pubmed-meshheading:14499864-Growth Inhibitors,
pubmed-meshheading:14499864-Humans,
pubmed-meshheading:14499864-Immunohistochemistry,
pubmed-meshheading:14499864-Interleukin-6,
pubmed-meshheading:14499864-Leukemia Inhibitory Factor,
pubmed-meshheading:14499864-Molecular Chaperones,
pubmed-meshheading:14499864-Myocarditis,
pubmed-meshheading:14499864-Myocytes, Cardiac,
pubmed-meshheading:14499864-Oncostatin M,
pubmed-meshheading:14499864-Organic Cation Transport Proteins,
pubmed-meshheading:14499864-Peptides,
pubmed-meshheading:14499864-Proteins,
pubmed-meshheading:14499864-RNA, Messenger,
pubmed-meshheading:14499864-Vascular Endothelial Growth Factor A
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pubmed:year |
2003
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pubmed:articleTitle |
Glycoprotein 130 ligand oncostatin-M induces expression of vascular endothelial growth factor in human adult cardiac myocytes.
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pubmed:affiliation |
Department of Internal Medicine II, University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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