Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
|
pubmed:dateCreated |
1992-12-29
|
pubmed:abstractText |
Herein we report the case of an ampullary tumor in a 53-yr-old Japanese woman who presented in March 1988 with abdominal pain, weight loss, and jaundice. A pancreatoduodenectomy was carried out, and 3 months later, she presented with a Virchow's node. She was initially treated with cytokines plus 5-fluorouracil derivative, resulting in a complete remission lasting over a year. However, in July 1990, the Virchow's node reappeared and was surgically excised. Histology revealed a small-cell neuroendocrine carcinoma (SCNC) similar to the prior ampullary tumor, which was confirmed by immunohistochemical studies and electron microscopic examination. The patient was discharged within 1 month, remaining disease-free over a 18-month period following excision. We suggest that the use of cytokines can be effective, and can increase survival in gastrointestinal neuroendocrine tumors.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0002-9270
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
87
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1810-2
|
pubmed:dateRevised |
2006-4-24
|
pubmed:meshHeading |
pubmed-meshheading:1449147-Ampulla of Vater,
pubmed-meshheading:1449147-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:1449147-Carcinoma,
pubmed-meshheading:1449147-Combined Modality Therapy,
pubmed-meshheading:1449147-Common Bile Duct Neoplasms,
pubmed-meshheading:1449147-Female,
pubmed-meshheading:1449147-Humans,
pubmed-meshheading:1449147-Interferon-alpha,
pubmed-meshheading:1449147-Middle Aged,
pubmed-meshheading:1449147-Neoplasm Recurrence, Local,
pubmed-meshheading:1449147-Remission Induction,
pubmed-meshheading:1449147-Survival Rate,
pubmed-meshheading:1449147-Tegafur,
pubmed-meshheading:1449147-Tumor Necrosis Factor-alpha,
pubmed-meshheading:1449147-Uracil
|
pubmed:year |
1992
|
pubmed:articleTitle |
Can cytokines prolong survival in ampullary neuroendocrine carcinomas?
|
pubmed:affiliation |
First Department of Surgery, Okayama University School of Medicine, Japan.
|
pubmed:publicationType |
Journal Article,
Case Reports
|