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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1992-12-15
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pubmed:abstractText |
Lysine influx (2 microM) into activated human B and T lymphocytes through transport systems y+ and y+L was measured. In activated T cells very substantial activation of system y+ was detected; system y+L was also activated in these cells but with a slower time course and to a smaller extent. No stimulation of either system was found in activated B cells. The time course of activation of system y+ precisely matched the expression of the T cell early antigen gene described by MacLeod et al, 1990. The functional significance of these observations with respect to L-arginine transport and nitric oxide synthesis in activated T lymphocytes is discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0031-6768
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
422
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
87-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1437528-Amino Acids,
pubmed-meshheading:1437528-Antigens, Differentiation, T-Lymphocyte,
pubmed-meshheading:1437528-B-Lymphocytes,
pubmed-meshheading:1437528-Biological Transport,
pubmed-meshheading:1437528-Cations,
pubmed-meshheading:1437528-Gene Expression,
pubmed-meshheading:1437528-Humans,
pubmed-meshheading:1437528-Lymphocyte Activation,
pubmed-meshheading:1437528-Lymphocytes,
pubmed-meshheading:1437528-Lysine,
pubmed-meshheading:1437528-T-Lymphocytes
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pubmed:year |
1992
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pubmed:articleTitle |
Activation of cationic amino acid transport through system y+ correlates with expression of the T-cell early antigen gene in human lymphocytes.
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pubmed:affiliation |
Department of Human Anatomy, University of Oxford, UK.
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pubmed:publicationType |
Journal Article
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