Linked Life Data

141875

Source:http://linkedlifedata.com/resource/pubmed/id/141875

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1977-8-25
pubmed:abstractText
The possible utilization of the effect of immunological tolerance for inhibition of formation of thromboagglutinins was studied, which dependent of the kind of antigen employed for immunization more or less contaminate antilymphocyte sera (ALS) or globulins (ALG). In the sera of pigs weighing 80-90 kg, immunized with human thrombocytes the thromboagglutinin levels in a) animals tolerated in adult age with an i.v. dose of 2.2 X 10(9) thrombocytes though the complete inhibition of thromboagglutinin formation failed even in these conditions. The attempted induction of tolerance in adult animals, similarly as in newborn piglets obtaining a dose of 1 X 10(9) thrombocytes, was of little success. Good results were recorded in animals tolerated in the perinatal period with a dose of 5 X 10(9) thrombocytes though the complete inhibition of thromboagglutinin formation failed even in these conditions. The authors suggest that of all possible methods for thromboagglutinin elimination, for ALS production the above technique, i.e. the induction of tolerance during the perinatal period seems most feasible, both from the viewpoint of effectiveness and thrombocyte consumption as well.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0323-4398
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
43-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
[About the elimination of thromboagglutinins from anti-lymphocytic serum (author's transl)].
pubmed:publicationType
Journal Article, English Abstract